منابع مشابه
Pancreatic Neuroendocrine Tumors
Pancreatic neuroendocrine tumors are usually indolent (slow-growing) by nature and develop over the course of many years. Pancreatic neuroendocrine tumors are usually more indolent, with better prognosis than adenocarcinoma of the pancreas (Carriaga & Henson, 1995). However, aggressive, fast growing pancreatic neuroendocrine tumors exist and different types of pancreatic neuroendocrine tumors e...
متن کاملBiomarkers in pancreatic neuroendocrine tumors.
The aim of biomarkers is to identify patients most likely to benefit from a therapeutic strategy. Pancreatic neuroendocrine tumors are rare neoplasms that arise in the endocrine tissues of the pancreas. Pancreatic neuroendocrine tumors represent 3% of primary pancreatic neoplasms and their incidence has risen. The SMAD4 gene is located on chromosome 18q and someday the SMAD4 gene status may be ...
متن کاملDiagnosis of Pancreatic Neuroendocrine Tumors
Pancreatic neuroendocrine tumors (PNETs) are relatively rare; however, the incidence has increased over the last few decades. They are classified as functional or non-functional tumors according to the presence of associated clinical symptoms. The majority are non-functional tumors. For classification and staging, the World Health Organization 2010 classification system is the most commonly acc...
متن کاملSystemic Therapies for Advanced Pancreatic Neuroendocrine Tumors.
Pancreatic neuroendocrine tumors are an uncommon tumor type and compose 1% to 2% of all pancreatic neoplasms. They are rarely localized at presentation and are typically diagnosed in the presence of metastatic disease. The management poses a significant challenge because of the heterogeneous clinical presentations and varying degrees of aggressiveness. A variety of systemic therapies have been ...
متن کاملDiagnostic protocol for pancreatic neuroendocrine tumors (PNETs).
A: angiography; US: ultrasonography; EUS: endoscopic ultrasonography; IUS: intraoperative ultrasonography; EUS-FNA: endoscopic ultrasonography-guided fine-needle aspiration; MRI: magnetic resonance imaging; SRS: octreoscan; CT: computerized tomography; MDCT: multidetector computerized tomography; PET: positron emission tomography; PET-CT: PET with computerized tomography; ICC: immunocytochemist...
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ژورنال
عنوان ژورنال: Nature Reviews Clinical Oncology
سال: 2011
ISSN: 1759-4774,1759-4782
DOI: 10.1038/nrclinonc.2011.33